英语释义

1. of, relating to, undergoing, or being a change in the shape and activity of a protein (such as an enzyme) that results from combination with another substance at a point other than the chemically active site

2. of, relating to, or being a change in the shape and activity of a protein (as an enzyme) that results from combination with another substance at a point other than the chemically active site

片语

allosteric site变构部位；别构部位

allosteric modification别构修饰

allosteric enzyme[生化] 变构酶；[生化] 别构酶

allosteric inhibition[生化] 异位抑制

allosteric ligand别构配体

allosteric effector异位效应物

allosteric effect[生化] 别构效应；[生化] 变构效应

allosteric theory变构学说

英汉例句

• many oligomer ic proteins are allosteric and known to be self-condensing and play an important role in metabolic control.

  许多低聚物蛋白是变构的并且是能自我压缩的，在对于新陈代谢中起着重要的作用。

• cyclin d1 which functions as a mitogenic sensor and allosteric activator of cdk4/6, is one of the more frequently altered cell cycle regulators in cancers.

  细胞周期蛋白d1作为一个能促进有丝分裂和cdk4的变构激活剂，是癌癥中较频繁变化的细胞周期调节子。

• the results indicated that the cmc method could be a new way for quantitative analysis of allosteric effects for 5-hydroxytryptamine receptor.

  该方法为定量研究受体的别构效应提供了一种全新思路。

• it is an allosteric enzyme .

  它是一个别构酶。

• conclusion: tricyclopinate inhibits neuronal nachr by interacting with the allosteric sites rather than the open ionic channels or acetylcholine recognition site of the receptor.

  结论：三环哌酯抑制神经元烟堿受体的作用部位在变构位点而不是在离子通道或乙酰胆堿识别位点。

• a fundamental goal in signal transduction study is to understand allosteric communication.

  构通讯的理解是研究细胞信号转导的一个基本目标。

• allosteric effects of hemoglobin;

  血红蛋白的变构效应；

• phosphorylation leads to inactivation of gs, but activity is restored by the binding of the allosteric activator glucose-6-phosphate, which induces its dephosphorylation and activation (4).

  磷酸化会抑制gs活性，但活性可被变异配体6-磷酸葡萄糖结合后恢复，6-磷酸葡萄糖可以诱导gs的去磷酸化从而激活。

• proteins which have two separate but interacting sites are called allosteric proteins.

  这种具有两个不同而又相互作用位置的蛋白质叫做变构蛋白质。

• proteins which have two separate but interacting kinding sites are called allosteric proteins.

  这种具有两个不同位置而又相互作用的蛋白质叫做变构蛋白质。

• a fundamental goal in signal transduction study is to understand allosteric communication.

  对变构通讯的理解是研究细胞信号转导的一个基本目标。

• gs is regulated by multi-site phosphorylation and by the binding of allosteric ligands.

  gs受到多个位点磷酸化的调控，同时也受变构配体结合的调控。