Objective To study the dynamic changes of S100B protein in subarachnoid aneurismal hemorrhage and investigate the clinical significance in the development of the disease.
The hemodynamic mechanism has been considered to be the main factor related to the cerebral aneurismal growth and rupture.
血液动力学机制被认为是导致脑动脉瘤生长乃至破裂的主要因素。
The wall of ruptured aneurysms was found to be fragile, possibly because macrophage infiltration into the aneurismal wall resulted in loss of smooth muscle cells and in degradation of matrix proteins.
破裂动脉瘤的瘤壁脆性增加,可能与平滑肌细胞缺失和基质蛋白降解而引起的炎性细胞浸润有关。
The wall shear stress formed under the impact of blood flow is most prominent in the neck of aneurysms than other locations and is weak in the aneurismal wall.
切应力由于血流沖击瘤壁形成,主要存在于瘤颈处且方向可变化,瘤壁很微弱;
As the hemodynamic factors have great relationship with aneurismal abiogenesis, it became the hotspot of aneurismal study in the world in recent years.