pegylated interferon
聚乙二醇干扰素
2026-04-13 23:35 浏览次数 23
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Pegylated Interferon-alpha-2a聚乙二醇干扰素
both we know are have some relapse (6.30) showing that the two drugs, the combination of the the potent analog and the pegylated interferon is synergistic in this way.
我们知道通过这种联合应用,核苷类药物和聚乙二醇干扰素能互相增效来抑制复发。
based on that study, i think it is right to think about combinations of pegylated interferon and tenofovir.
基于该研究结果,我认为可以考虑联合聚乙二醇化干扰素和替诺福韦的进行治疗。
hepatology digest: professor, as far as on going studies in china is concerned, what is your idea of this analog and pegylated interferon combination?
《国际肝病》:教授,就目前在中国进行的研究来讲,您对核苷类药物和聚乙二醇干扰素联合应用的看法如何?
pegylated interferon alpha and ribavirin lead to a sustained response in approximately 50% of patients.
乙二醇干扰素和利巴韦林导致持续反应大约50%的病人。
however, we still have some patients taking pegylated interferon alpha-2b.
然而,我们还对有些患者应用聚乙二醇干扰素α-2b。
these two studies show that these drugs combine with pegylated interferon and ribavirin increases in terms of sustained response.
有关这两种药物的研究显示,这些药物联合聚乙二醇干扰素和利巴韦林应用能增加持续病毒应答。
role of a 48-week pegylated interferon therapy in hepatitis be antigen positive hiv-co-infected patients on cart including tenofovir: emvipeg study.
【译】一个48周聚乙二醇干扰素治疗乙型肝炎e抗原阳性hiv共感染患者车包括替诺福韦的作用:emvipeg研究。
professor wei: actually, we have an ongoing trial for the combination of pegylated interferon alpha-2a and adefovir.
魏来教授:实际上,我们正在进行联合应用聚乙二醇干扰素和阿德福韦的研究。
in recent years, as part of the search for improved treatment, pegylated interferon alfa, which is a longer acting form of interferon alfa, has been studied.
近年来,peglated干扰素(一种干扰素a的长效剂型)作为寻找改进治疗过程中的一个收获,被广泛研究。
both of these groups pose challenges because historically their response to pegylated interferon is inferior to those immunocompetent patients.
这些患者都向我们提出了挑战,因为从病史来看他们对聚乙二醇干扰素的治疗应答不如免疫功能正常的患者。
phase ii studies will provide insight into the necessity to couple protease inhibitors and pegylated interferon with or without ribavirin.
二期研究的重点将集中在联合应用蛋白酶抑制剂和聚乙二醇化干扰素时是否需要加用病毒唑上。
combined treatment with pegylated interferon (peg-ifn) and ribavirin is currently recommended for the treatment of chronic hepatitis c virus (hcv) infection.
目前推荐聚乙二醇干扰素和利巴韦林是联合治疗用于治疗慢性丙型肝炎病毒感染。
could we extend the treatment of pegylated interferon and ribavirin and perhaps reduce the incidence of relapse?
我们可否通过延长聚乙二醇干扰素和利巴韦林治疗来降低复发率?
pegylated interferon plus telbivudine, but this combination can not be used as this combination induces toxicity, neuropathy. so it is not right to mention it.
聚乙二醇干扰素加替比夫定,但这种联合不能应用,因为会导致神经系统毒性反应。
could you please tell us a little bit about the mechanism of pegylated interferon alpha-2a antiviral therapy and is it different to the mechanism of pegylated interferon alpha-2b?
您能否谈下聚乙二醇干扰素α-2a治疗的作用机制,它和干扰素α-2b的作用机制是否有不同呢?
usually for this co-infection population we first treat the hiv with haart therapy and induce the cd4 cells then we will treat the co-infection of hcv with pegylated interferon and ribavirin.
通常对这类混合感染者,我们首先用高效抗逆转录病毒治疗、诱导cd4细胞等疗法治疗艾滋病毒,然后我们用聚乙二醇干扰素联合利巴韦林治疗混合感染的丙肝病毒。
when we use the combined therapy of pegylated interferon and ribavirin, we are just using something to prevent a relapse and to obtain a long response.
会不会出现新的耐药呢?我们只用干扰素和利巴韦林进行联合治疗的时候,我们只是用一些防止复发、获得长效应答的药物。
probably in the future, pegylated interferon will continue to be a good way to treat e-negative patients.
或许在未来,聚乙二醇干扰素依旧是治疗e抗原阴性患者的好方法。
international digest: for hepatitis c patients being treated with pegylated interferon and ribavirin, how can we improve the svr? do you have any suggestions or advice for us?
国际肝病:对于正在接受聚乙二醇干扰素和利巴韦林治疗的丙肝患者,您能给我们一些提高持续病毒学应答的建议吗?
so if they choose to use a high dose of pegylated interferon alpha-2b, they may have to pay out of their own pocket.
如果他们选择用高剂量的聚乙二醇干扰素α-2b,他们可能要自己掏钱。
in these so-called difficult-to-treat cases you have to either increase the dose of pegylated interferon or the dose of ribavirin or in the future perhaps we can add protease inhibitors.
对于这些所谓难治性的病例,你必须增加聚乙二醇干扰素或者利巴韦林的剂量,或许在未来可能加用蛋白酶抑制剂进行治疗。
the patient is just treated with pegylated interferon alpha-2a because there is no need to adjust the dosage for the patients.
对没有调整剂量需要的患者,我们只用聚乙二醇干扰素α-2a治疗。
since january 2009 it has been working with bristol-myers to develop a potential hepatitis c treatment called pegylated interferon lambda.
自2009年1月份以来,zymogenetics已同百时美施贵宝展开合作,双方试图联合开发一种用于治疗丙型肝炎的药物pegylated interferonlambda。