aim: to study the basic mechanism of transcriptional regulation, nkx3.1 gene promoter was cloned and its promoter activities in prostate cancer cell lines and other cancer cell lines were tested.
目的:克隆nkx3.1基因启动子并检测其启动子活性,为研究nkx3.1基因转录调控的基本机制奠定基础。
methods the gene was cloned by improved pcr based subtractive hybridization from apoptotic prostate cancer cell line du 145 cells induced by atra.
方法应用全反式维甲酸诱导前列腺癌细胞系du- 1 45细胞凋亡,采用基于pcr的改良消减杂交技术克隆与凋亡相关的基因。
objective: to culture and establish chinese ethnic prostate cancer cell line, investigate its growth characterization and explore experimental methods and models of gene diagnosis and trial of drugs.
目的:培养建立中国人种前列腺癌细胞系,为了解中国人种前列腺癌细胞生长特性、进一步开展前列腺癌基因诊断和药物筛选建立方便的实验手段和模型打下基础。
aim: to study the role of androgen receptor (ar) in hormone-dependent and hormone-independent prostate cancer cell proliferation by knocking down ar expression with adenovirus-delivered sirna.
目的:利用rna干涉技术抑制雄激素受体(ar)的表达,研究ar在激素依赖性和激素非依赖性前列腺癌细胞增殖中的作用。
used a mouse xenograft model where a human prostate cancer cell line was implanted into mice to show that there were tumor-derived mirnas circulating in blood.
大约在同一时间,mitchell等人将人前列腺癌细胞输入作为异种移植物模型的小鼠体内,从而证明了循环中含有肿瘤来源的microrna。
around the same time, mitchell et al. used a mouse xenograft model where a human prostate cancer cell line was implanted into mice to show that there were tumor-derived mirnas circulating in blood.
大约在同一时间,mitchell等人将人前列腺癌细胞输入作为异种移植物模型的小鼠体内,从而证明了循环中含有肿瘤来源的microrna。
glucosamine appears to inhibit il-1b-mediated map kinase phosphorylation to reduce il-8 expression, and therefore to retard prostate cancer cell proliferation and migration.
而氨基葡萄糖可能会藉由抑制mapk路径的磷酸化来减缓介白素-8的表现,进而来降低摄护腺癌细胞之增生及转移。
objective to study the possible association between granulocyte-macrophage colony stimulating factor (gm-csf) and the telomerase activity of human prostate cancer cell line pc-3m.
目的研究粒细胞巨噬细胞集落刺激因子(gmcsf)对前列腺癌pc3m细胞株端粒酶活性的影响。
bergan and his team have previously demonstrated in prostate cancer cell cultures that genistein inhibits detachment of cancer cells from a primary prostate tumor and represses cell invasion.
bergan及其研究小组以前就证实过在前列腺癌细胞培养中高金雀花堿可抑制癌细胞从原始前列腺肿瘤中分离和抑制肿瘤细胞侵袭。