The investigators used a combination of experiments with mouse models and test tubes to study the effects of intestinal inflammation on Salmonella and pinpoint the role of tetrathionate respiration.
「Stimulating the host to produce tetrathionate enables Salmonella to 「breathe」 in the intestine,」 said Sebastian e.
「刺激宿主去制造连四硫酸盐,使得沙门氏菌在肠里呼吸,」Sebastiane。
But because tetrathionate was not known to exist in living people, it was assumed prior to this study that this process had little relevance for food poisoning.
但是因为连四硫酸盐当时未被知晓存在于活体中,这个过程与食物中毒没有关系,早于该项研究,被假定了。
Finding that tetrathionate is important in human Salmonella infection opens up new avenues for research in finding an effective treatment for salmonellosis.