alzheimer disease
阿尔茨海默病;老年癡呆癥
2026-05-05 13:43 浏览次数 16
阿尔茨海默病;老年癡呆癥
1. a degenerative brain disease of unknown cause that is the most common form of dementia, that usually starts in late middle age or in old age, that results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood, and that is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid
Behavioral problems, such as mood swings and agitation, may also be a part of the progression of Alzheimer's disease.
— Allan Perel … the ability to differentiate normal aging-related memory changes from the impairments associated with dementia, including Alzheimer disease …
— C. Munro Cullum … researchers in California have created mice carrying the gene for beta-amyloid protein, the principal component of the plaques riddling the brains of people with Alzheimer's.
— Charlene Crabb Note: Alzheimer's is often used before another noun.
Alzheimer's patients —abbreviation AD
2. a disease of the brain that causes people to slowly lose their memory and mental abilities as they grow old
3. a degenerative brain disease of unknown cause that is the most common form of dementia, that usually starts in late middle age or in old age, that results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood, that leads in advanced cases to a profound decline in cognitive and physical functioning, and that is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid
Behavioral problems, such as mood swings and agitation, may also be a part of the progression of Alzheimer's disease.
— Allan Perel, The Staten Island (New York) Advance, 12 Nov. 2007 Alzheimer disease (AD) is the most common cause of dementia, affecting more than 15 million individuals worldwide.
— Niklas Mattsson et al., The Journal of the American Medical Association, 22 July 2009 … researchers in California have created mice carrying the gene for beta-amyloid protein, the principal component of the plaques riddling the brains of people with Alzheimer's.
— Charlene Crabb, U.S. News & World Report, 4 Nov. 1991 —abbreviation AD
objective to investigate the effect of no. 1 recipe on learning and memory function of spontaneous alzheimer disease models.
目的:观察天泰1号对自发阿尔茨海默病模型学习记忆功能的影响。
objective to explore the effect of mutation of presenilin 1 (ps 1) gene on the pathogenesis of familial alzheimer disease (fad).
目的探讨早老素1基因突变在家族性阿尔茨海默病(fad)发病中的作用。
background: low education is a well known risk factor for alzheimer disease (ad).
背景:低教育程度是阿尔茨海默病(ad)公认的危险因素。
more good news, there is evidence of a lower risk of developing alzheimer disease as well as a reduction in the probability of developing type 2 diabetic diseases.
更好的是,有证据表明:鱼类和海鲜的摄入能够降低阿尔茨海默病的发病风险,和减少2型糖尿病发病的概率。
context genome-wide association studies (gwas) have recently identified clu, picalm, and cr1 as novel genes for late-onset alzheimer disease (ad).
全基因组相关性研究新近确定了clu,picalm和cr1是晚发性阿尔茨海默氏病(ad)的新相关基因。
objective: to assess the effect of parallel intervention of cognitive training and supports of caregivers for alzheimer disease (ad) patients.
评价阿尔茨海默病(ad)病人认知训练与家庭照顾者支持相结合平行干预的效果。
context emerging data suggest that psychological and experiential factors are associated with risk of alzheimer disease (ad), but the association of purpose in life with incident ad is unknown.
研究数据表明心理学和经验方面的因素都与ad(阿尔茨海默病)的发生风险相关,但人生目标与ad发病率的关联却不清楚。
conceivably, such delay could result in increased incidence of alzheimer disease incidence in late old age.
但可以想象的是,这种延迟将导致在后来的老年时阿尔茨海默氏病发病率的增加。
results: according to intention-to-treat analysis, all the 135 patients with alzheimer disease and 138 health controls entered the analysis of results.
结果:按意向处理分析,135例阿尔茨海默病患者和138名正常健康人均进入结果分析。
it is suggested that acidic peptide improves learning and memory of rat with alzheimer disease probably by inhibiting the synthesis of toxic compound of no or its toxicity.
提示酸性肽可能是通过抑制一氧化氮等毒性化合物的生成或毒性作用来提高阿尔茨海默病模型大鼠的学习记忆能力。
background: alzheimer disease (ad) and vascular dementia (vd), the two major types of dementia in old age, differ from each other in pathological mechanism, treatment and prognosis.
背景:阿尔茨海默病和血管性癡呆是老年期癡呆的两个主要类型,两者的发病机制不同,治疗与预后也不相同。
objective:to investigate the characteristic of plasma lipid in alzheimer disease (ad) and vascular dementia (vd) and mild cognitive impairment (mci).
目的:研究阿尔茨海默病(ad)、血管性癡呆(vd)及轻微认知功能损害(mci)患者血脂水平的特点。
about 35% patients with senile depression had cognitive impairment, and 17%-29% patients with alzheimer disease had depression.
大约35%老年抑郁癥患者具有认知损害,17%- 29%阿尔茨海默病患者患有抑郁癥。
fimbria-fornixs of brain were transected and bilateral ovaries were cut off to establish models of alzheimer disease accompanied by decreased level of estrogen in vivo.
所有大鼠在脑立体定位仪上切断穹隆-海马伞,并切除双侧卵巢,建立模拟伴有体内雌激素水平下降的阿尔茨海默病动物模型。
methods:the analysis is carried on the interrelationship between kidney turbidity and alzheimer disease in the aspects of pathology, pathogenesis and clinical manifestations.
方法:从病理变化,发病机制,临床表现等几个方面对肾浊与阿尔茨海默病的关系进行分析。
objective to explore the incidence of dementia and alzheimer disease (ad) and the impact of gender, age and education.
目的调查癡呆和阿尔茨海默病(ad)的发病率及其与性别、年龄、教育程度的关系。