to investigate the impact of amphotericin b liposome( amphotec ) on the rabbits' hepatic and renal functions.

目的研究脂质体两性霉素b对家兔肝肾功能主要生化指标的影响。

conclusion: amphotericin b associated rta is related to the dosage of amphotericin b and the concurrent medications of nephrotoxic drugs.

结论：rta的发生和两性霉素b的剂量、肾毒性药物的合用有关。

our study indicates that if it is used properly and hepatic and renal function tests are carried out regularly, amphotericin b is a relatively safe and effective drug.

我们的研究表明：只要合理用药，定期监测肝肾功能，该药仍是一相对较为安全有效的药物。

the drug sensitive test in vitro indicated that itraconazole, amphotericin b and nystatin were highly sensitive, ketoconazole and clotrimazole were low sensitive, fluconazole was resistant.

体外药敏试验显示对伊曲康唑、两性霉素b、制霉菌素高度敏感，酮康唑、克霉唑低度敏感，氟康唑耐药。

a possible combination therapy , such as fluconazole and amphotericin b liposome, should be emphasized in the future research.

进一步应重视联合治疗的可能性，例如使用氟康唑加二性霉素b脂质体。

micafungin combined with voriconazole or amphotericin b was the most effective, these being the only treatments able to prolong survival and to reduce the fungal load in the kidneys and brain.

米卡芬凈与伏立康唑或两性霉素b联合最有效，并且是唯一能够延长存活期并减少肾脏和脑部真菌负荷的治疗策略。

methods by referring to the recent literatures, the mechanism of action and clinical applications of amphotericin b in ophthalmology is reviewed.

方法参考近年来的文献，论述两性霉素b的作用机制及在眼科中应用。

furthermore, the patients with positive gm test received preemptive antifungal therapy with amphotericin b or itraconazole.

对gm实验阳性的患者给予两性霉素b或伊曲康唑抢先抗曲霉治疗。

objective:to establish an hplc method for the determination of amphotericin b (amb) in rabbits plasma and investigate the pharmacokinetic characteristics of amb by intravenous administration.

目的：建立血浆中两性霉素b浓度的hplc测定方法，并用此方法研究两性霉素b在家兔体内的药动学。

objective to study the stability of the liposomal amphotericin b preparation by extruding linkage device.

目的考察挤压器联动装置制备两性霉素b脂质体制剂的稳定性。

amphotericin b liposome can effectively control ifi after sbtx. with closely surveillance of recipient renal function, high dose of amphotericin b liposome can be safely used.

两性霉素b脂质体能够成功救治ifi患者，在严密监测肾功能下，大剂量应用两性霉素b脂质体是安全的。

amphotericin b liposome has good effect on infection of ochroconis gallopava.

两性霉素b脂质体治疗本病疗效显着。

the appropriate dose and method of administration differ markedly between the marketed parenteral formulations of amphotericin b and they are therefore not interchangeable.

在已上市的两性霉素b注射用制剂中，其给药剂量和方法有明显不同，因此不能替换使用。

amphotericin b and nystatin, ketoconazole and clotrimazole have been known to have similar antifungal mechanism respectively.

两性霉素b和制霉菌素、酮康唑和克霉唑都是已知的作用机制类似的抗真菌药物。

aimto study the therapeutic efficiency of amphotericin b liposome( amb-l) targeting to the brain in mice with meningitis.

目的研究两性霉素b脑靶向脂质体对小鼠脑膜炎的治疗作用。

methods the amphotericin b liposome was prepared by the film-supersound method.

方法用薄膜超声法制备两性霉素b脂质体；

conclusion amphotericin b is an essential antifungal agent for treating ocular fungal infections and its liposomes possesses a good applied perspective.

结论两性霉素b是临床上不可缺少的抗真菌药物，两性霉素b脂质体在治疗眼部真菌感染具有良好的应用前景。

amphotericin b liposome and itraconazole are effective in treating penicilliosis marneffei.

两性霉素b脂质体及伊曲康唑治疗有效。

aim: to observe the influence on peripheral blood figure by amphotericin b (amb) combined with flucytosine (5 fc) in the treatment of the patients with cryptococcus meningitis.

目的：探讨两性霉素b（amb）联合5 -氟胞嘧啶（5 -fc）治疗新型隐球菌性脑膜炎时对患者外周血象的影响。

amphotericin b diffusion studies were performed via excised rabbit skin using a drug diffusion apparatus. the contents of amphotericin b were measured by hplc.

用药物渗透扩散仪进行两性霉素b透皮吸收研究，高效液相色谱法测定两性霉素b含量。

amphotericin b overdoses may result in potentially fatal cardiac or cardiorespiratory arrest.

两性霉素b过量可能导致潜在致命性的心跳或心跳呼吸停止。

objective to compare the antifungal activities of voriconazole against candida krusei with fluconazole and amphotericin b in vivo.

目的比较伏立康唑、氟康唑和两性霉素b在体内对克柔念珠菌的抗真菌活性。

objective to study the formulation and preparation of amphotericin b liposomes(lamb), and evaluate its quality.

目的 对两性霉素b脂质体的处方和制备工艺进行研究，并评价其质量。