suppressive role of tolerant spleen cells adoptively transferred in vivo and in vitro was tested by dth and mlr. meanwhile the role of t cells clonal anergy was also detected.
检测体内、外过继转移耐受大鼠脾细胞对正常大鼠单向混合淋巴细胞反应(mlr)和迟发性过敏反应(dth)的抑制作用,以及t细胞克隆不应答在耐受中的作用。
clonal anergy and suppressor cells are main mechanisms of the tolerance.
克隆不应答和抑制细胞是耐受的主要机制。
several other mechanisms may by theorized for the induction of tolerance in this renal transplant model, including clonal anergy and suppressive cells.
结论嵌合状态与肾移植耐受存在明显相关性,克隆不应答、抑制细胞参与了耐受的形成。