It is necessary to establish a hypoxia model for HIF and to perform further hypoxia tolerance research.
有必要建立一种相关缺氧模型,用于HIF和缺氧耐受性的研究。
Employing genetic manipulation of HIF expression, in-vivo and cellular studies have focused on HIF as a crucial factor affecting hypoxia-induced vascular remodeling.
体内以及细胞研究的低氧诱导因子表达主要焦点在低氧诱导分子作为一种影响低氧诱导血管重建的重要因子。
In this review, we summarize and discuss mechanisms by which HIF interferes with the different vascular remodeling processes.
在此综述中,我们总结并讨论了有关低氧诱导因子干预不同血管重建过程的机制。
This paper reviews the production of ROS and its role in the regulation of HIF activity.
本文主要就ROS的产生及其对HIF活性调节方面的文献进行综述。
HIF - 1 could become an effective target for cancer treatment in the near future.