A capillary GC method with FID detector for the determination of residual organic solvents ethanol, isopropanol, dichloromethane, n-hexane, tetrahydrofuran, DMF and dimethyl malonate was established.
Methods: the title compounds were synthesized from malonate and p-cresol. Orthogonal test was carried out to find out the optimal condition.
方法:以丙二酸和对甲酚为原料合成目标化合物,用正交试验摸索最优条件。
A competitive inhibitor is usually structurally similar to the substrate, e. g. malonate is a competitive inhibitor of the enzyme succinate dehydrogenase.
与底物结构相似的物质能竞争性的与酶结合,从而使酶不能与底物结合而丧失其催化活性。
First we synthesized the -phenylethyl chloride from -phenylethyl alcohol. Then it was substituted by enolate anion of diethyl malonate and converted to ester.
在我们的合成方法中,先从-苯乙醇开始合成了-苯乙基氯,再用丙二酸二乙酯的烯醇盐离子进行亲核取代。
In a traditional synthesis method with malonate ester as the raw material, impurities are produced in the finally obtained biotin.
目前用丙二酸二酯作原料的合成方法,在最后得到的生物素中会伴随杂质的产生。
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