T-cell receptor中文，T-cell receptor的意思，T-cell receptor翻译及用法

2025-11-01 20:34 浏览次数 13

T-cell receptor

The T cell receptor or TCR is a molecule found on the surface of T lymphocytes (or T cells) that is responsible for recognizing antigens bound to major histocompatibility complex (MHC) molecules. The binding between TCR and antigen is of relatively low affinity and is degenerate: that is, many TCR recognize the same antigen and many antigens are recognized by the same TCR.

T-cell receptor 英语释义

英语释义

    1. an antigen receptor on the surface of a T cell that is composed of two transmembrane polypeptide chains covalently linked by disulfide bonds and that initiates T cell activation upon binding with a specific antigenic peptide fragment combined with a major histocompatibility complex molecule and displayed on the surface of an antigen-presenting cell
    … the T cell receptor actually recognizes not a solitary peptide but a complex consisting of a peptide and the surrounding region of the class I MHC molecule.
    — Thierry Boon … the T-cell receptor … acts as the antigen receptor for T cells one of whose principal functions is to recognize and destroy virus-infected cells …
    — Carl Branden et al. — abbreviation TCR

    2. an antigen receptor on the surface of a T cell that is composed of two transmembrane polypeptide chains covalently linked by disulfide bonds and that initiates T cell activation upon binding with a specific antigenic peptide fragment combined with a major histocompatibility complex molecule and displayed on the surface of an antigen-presenting cell
    … the T cell receptor actually recognizes not a solitary peptide but a complex consisting of a peptide and the surrounding region of the class I MHC molecule.
    — Thierry Boon … the T-cell receptor … acts as the antigen receptor for T cells one of whose principal functions is to recognize and destroy virus-infected cells …
    — Carl Branden et al. — abbreviation TCR

T-cell receptor 例句

英汉例句

  • Objective: to investigate the anti-tumor effects of murine T-lymphocytes harboring p185HER2 specific chimeric T-cell receptor gene.

    目的：研究小鼠t淋巴细胞在转染嵌合性T细胞受体基因后的体外抗肿瘤作用。

  • The positive rate of T-cell receptor gene rearrangement was 81.3%, and was independent of the histological features.

    细胞受体基因重排的阳性率为81.3%，阳性率与疾病分期无关。

  • 「These structures, as well as other experiments we did, showed that the T-cell receptor USES a completely different recognition mechanism for the foreign and self MHC-protein complex,」 said Garcia.

    Garcia说，这些结构，与我们在其他实验中做的同样好，表现出T细胞受体对异体和自体MHC -蛋白复合物使用完全不同识别机制。

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