The dose limiting toxicity (DLT) of it was neutropenia and diarrhea. Its maximum tolerance dose (MTD) may be reduced by elevated liver or kidney function.
其剂量限制毒性(DLT)为中性粒细胞减少和腹泻,肝肾功能下降会降低最大耐受剂量(MTD)。
To observe the acute toxicity and death of the mice to which calcium nanoparticles were given in maximal dose and obtain the lethal dose 50(LD50) or the maximal tolerance dose (MTD).