the key of antibody-mediated immunological therapy is strong specificity of target antigen, low immunogenicity, high affinity of antibody and so on.
而抗体介导的免疫治疗的关键是靶抗原的特异性强,抗体的免疫原性低及亲和力高等。
conclusion with the increase of the immunization times, the affinity of antibody come to mature and the proportion of dominant linear epitopes of bsa became higher.