model high-fat group were divided into intervention group and non-intervention group, intervention approach to drug intervention by gavage for 8 weeks.
模型建立后将高脂组大鼠分为干预组与非干预组,干预组采用灌胃方式进行药物干预8周。
resultsin the experiment of acute toxicity, the maximum tolerance dosage by gavage in mice was 160 times of the clinical dosage in humans.
结果急性毒性实验小鼠灌胃给药最大耐受量相当于人临床日用量的160倍。
methods: the experiment research is that: give medicine to chronic hepatic-damnification rats through administration by gavage and coloclysis, observe the levels change of serumal transaminase.
方法:实验研究通过对慢性肝损伤大鼠采取灌胃与灌肠两种途径给药,观察其用药前后血清转氨酶等指标的改变。