NIH 3T3 cells were transfected by human papillomavirus 18(HPV 18). HPV 18 DNA as donor and calf thymus DNA as vector. Calcium phosphate technique was used.
Result:The Soot extraction can lead to interstrand DNA cross-links in calf thymus DNA and pulmonary cell DNA and there is the dose-responsive increase.
结果:煤烟颗粒提取物可以导致小牛胸腺DNA和大鼠肺细胞DNA产生交联,并存在剂量-反应关系。
Objective to study the cross-link effect on DNA and the toxic mechanism of acrylonitrile (an) using calf thymus DNA and spermatids of an exposed mice.