英语释义

1. an alkaloid C20H16N2O4 from the wood of a Chinese tree (Camptotheca acuminata of the family Nyssaceae) that has shown some antileukemic and anticancer activity in animal studies also a semisynthetic or synthetic derivative of this

片语

camptothecin sodium喜树堿钠

camptothecin syntheticintermediate喜树堿合成中间体

camptothecin analogues喜树堿及其衍生物

camptothecin distribution形态分布

camptothecin production喜树堿

camptothecin derivatives喜树堿类药物

camptothecin review喜树堿综述

s camptothecin喜树堿

camptothecin analog喜树堿衍生物

英汉例句

• in vivo camptothecin remains a balance of e-lactone form and carboxylic salt form.

  喜树堿在体内存在内酯环形式和羧酸盐形式的平衡。

• camptothecin was isolated in 1966, but its use was hampered by its poor water solubility.

  喜树堿早在196 6年就已经被分离出来，由于水溶性差而阻碍了对它的使用。

• result the problems of camptothecin such as solubility, stability and side effects could be solved by special delivery methods and strategies.

  结果通过一些特殊的传递方法与策略，可以解决喜树堿类药物所存在的溶解度、稳定性、毒性和不良反应等问题。

• camptothecin is a kind of anti-cancer activity of terpene indole alkaloids. camptothecin has important uses and research value.

  喜树堿是从我国特有植物喜树中分离到的一种具有抗癌活性的萜类吲哚生物堿，具有重要的利用和研究价值。

• objective:to explore the effect of hydroxy camptothecin on colorectal carcinoma cells in vitro.

  目的探讨羟基喜树堿对肠癌细胞的体外作用。

• camptothecin was coupled with 2-furonic acid, pyridinecarboxylic acid, niacin and isonicotinic acid through ester bond.

  喜树堿与呋喃甲酸、吡啶甲酸、烟酸和异烟酸通过酯键进行偶联。

• exogenous aba proved to pose negative effects on osmotic materials accumulation and antioxidant enzymes'activity, however, with no marked effects on camptothecin content.

  外源aba的使用可以缓解因为渗透胁迫引起的渗透调节物质含量和抗氧化酶类活性变化，但是对喜树堿含量并没有显着影响。

• objective to investigate the effect of camptothecin (cpt) on the inhibition of proliferation and induction of apoptosis of human umbilical vein endothelial cell line, ecv304, in vitro.

  目的探讨喜树堿在体外对人脐静脉血管内皮细胞ecv304增殖抑制和凋亡诱导作用。

• tryptophan synthase (tsb) and tryptophan decarboxylase (tdc) are two key enzymes in camptothecin biosynthetic pathway as they links primary and secondary metabolism.

  色氨酸合成酶（tsb）和色氨酸脱羧酶（tdc）是喜树堿合成过程中连接初生代谢和次生代谢过程的两个关键酶。

• results demonstrated that taxol, harringtonine, homoharringtonine and camptothecin exhibited significant inhibition of cell growth of b16bl6 and ht1080 cells.

  结果表明紫杉醇、三尖杉酯堿、高三尖杉酯堿及喜树堿对b16bl6和ht1080细胞增殖均有很强的抑制作用。

• therefore, derivatives of camptothecin are becoming the focus of research.

  因而喜树堿衍生物成为研究的热点。

• objective:to observe the therapeutic and side effects of intravesical infusion with hydroxyl camptothecin in treatment of late stage and postoperative recurrent bladder cancers.

  目的：观察羟基喜树堿膀胱内灌注治疗晚期膀胱癌和膀胱癌术后复发患者的治疗效果与不良反应。

• camptothecin and its derivatives are alkaloids possessing anti tumor activities.

  喜树堿及其衍生物是一类具有抗癌活性的生物堿。

• objective to review some delivery systems for camptothecin and its analogs in recent years.

  目的对喜树堿类药物的一些特殊传递系统进行综述。

• this invention provides a new camptothecin derivative with anti-tumor activity and structure as the right formula dissolving in water, its application, and its drug combinations.

  本发明提供一类具有以右式结构式所示结构的新的具有抗肿瘤活性 的能溶于水的喜树堿衍生物及其应用、以及包括该化合物的药物组合 物。

• through reviewing the process of developing camptothecin and its derivatives, to discuss its philosophy meanings and the value to development of other plant drugs.

  通过对喜树堿类药物研发过程的历史回顾，探讨其存在的哲学意义和对其它植物药研发的价值。

• it showed that arbuscular mycorrhiza did not improve the accumulation of camptothecin in all roots, but mainly improved in tertiary roots and fourth roots.

  由此表明，丛枝菌根对喜树幼苗根部喜树堿积累的促进作用主要表现为三、四级根喜树堿含量的增加。

• conclusion as the development and maturation of some novel drug delivery system, camptothecin will be a kind of potential anticancer drugs.

  结论随着新的药物传递系统的不断成熟与发展，喜树堿类药物将是十分有潜力的一类抗肿瘤药物。

• tryptophan synthase (tsb) and tryptophan decarboxylase (tdc) are two key enzymes in camptothecin biosynthesis as they link primary and secondary metabolism.

  色氨酸合成酶（tsb）和色氨酸脱羧酶（tdc）是喜树堿合成过程中连接初生代谢和次生代谢过程的两个关键酶。

• results suspension culture cells grew well in ms medium and cell homogeneity and camptothecin content were superior to those in other media.

  结果悬浮培养细胞在m s培养基中细胞生长良好，细胞分散性和喜树堿积累优于在其他培养基中。