英语释义

1. of, relating to, or produced by the chain of developmental processes in epigenesis that lead from genotype to phenotype after the initial action of the genes

2. relating to, being, or involving changes in gene function that do not involve changes in DNA sequence
epigenetic inheritance

3. formed after the laying down of the enclosing rock

4. of, relating to, or produced by epigenesis
the epigenetic nature of vertebrate development

5. relating to, being, or involving a modification in gene expression that is independent of the DNA sequence of a gene
epigenetic carcinogenesis epigenetic inheritance Methylation is one of many epigenetic signals—chemical changes to DNA and its associated proteins—that modify gene activity without altering the genetic information itself.
— Tina Hesman Saey, Science News, 14 Feb. 2009

片语

epigenetic inheritance基因调控的遗传

epigenetic modification后天性饰变

epigenetic factors表观遗传因子

hysterogenic致癔病的，后生的

epigenetic reprogramming遗传外重新编程

exogenous外生的；外因的；外成的

epigenetic deposit后成矿床，[地质] 后生矿床

epigenetic memory表观遗传记忆

epigenetic momentum后生动量

Epigenetic Markers表观遗传学标志物

epigenetic regulation后成调节

英汉例句

• in a second study, researchers found that rats raised by stressed mothers that neglected and physically abused their offspring showed specific epigenetic modifications to their dna.

  在另一项研究中，研究者们用压力大的母鼠以忽视或虐待的方式抚育幼鼠，随之发现幼鼠的dna有了特殊的表观遗传变化。

• but epigenetic changes are not typically as stable as changes in dna sequence.

  但表观基因组的变异并不如dna序列的改变那么稳定。

• free radicals provide a very good case study of how epigenetic processes play out.

  自由基为研究表观遗传过程的发生提供了很好的例子。

• environmentally triggered alterations in genes — known as epigenetic changes — can affect when a gene is activated, how robustly it is turned on and how it interacts with neighboring genes.

  环境所引发的基因变异被称为「表观遗传变化」，它可能会影响基因被激活的时间、被激活的程度以及它如何与邻近基因相互配合。

• it may be that epigenetic changes could be reinforced by mutations in the dna, making them stable and heritable in the conventional way.

  也许表观基因变异会因dna突变而得到强化，且由此变得稳定并以常规方式遗传下去。

• this suggests that if women drink too much in pregnancy, epigenetic changes may cause some of the permanent symptoms seen in fetal alcohol syndrome in their children.

  这表明，妇女如果在孕期饮酒过多，表观遗传变异可能会导致他们的子女出现胎儿酒精综合征中的一些固定癥状。

• epigenetic changes are heritable changes to the regulation of a cell’s genes, caused by extra molecules being attached to those genes.

  表观遗传变异是由附属于基因的其他分子作用引起基因表达改变的可遗传的变异。

• in some cases, epigenetic changes in people seem to be passed on to subsequent generations.

  在某些情况下，人类的表观遗传变异似乎会传递给后代。

• the 2007 pilot results were eye-opening: chromosomes harbored many previously unsuspected sites where various proteins bound—possible hotbeds of gene regulation or epigenetic effects.

  2007年的试验结果令人眼界大开：染色体上藏着许多以前不为人知的位点，那里结合着各种各样的蛋白——可能是基因调控和表观遗传效应的温床。

• but it’s hard to tell in most natural populations whether inheritance is due to dna sequence variation or epigenetic changes.

  但在自然界大多数种群中，很难判断遗传是否源于dna序列改变或者表观基因变异。

• chong says she doesn't know whether epigenetic modifications due to alcohol are passed onto the next generation of mice, but she hopes to find out in upcoming studies.

  chong说，她不知道动物实验中由酒精导致的表观遗传修饰是否会传递给下一代，她希望能在未来的研究中有所发现。

• in the past decade, researchers have made great strides in understanding the cellular, molecular, genetic, and epigenetic processes involved in the regulation of the stress response.

  在过去的十年里，研究人员在压力反应的细胞进程、分子进程、基因进程和后生过程的研究方面都有突飞猛进的发展。

• if the clone reaches maturity and reproduces naturally, epigenetic changes will often be reset, returning the sperm and egg nuclei to a state in which they can differentiate into all types of tissue.

  如果克隆成熟并可以自然繁殖，表观遗传变化常常会被重置，回到精子和卵细胞核的状态~可以变成所有类型的组织。

• however, he cautions, there is no direct evidence of this, and no specific evidence that the behaviors are transmitted through epigenetic mechanisms.

  不过，他也提醒，目前尚没有直接证据证明上述理论，也没有明确证据证明行为的继承是通过表观遗传机制实现的。

• the process, known as dna methylation, is one mechanism of epigenetic change, heritable change that does not alter the sequence of dna itself.

  该过程被成为dna甲基化，是表观遗传变化的一种，属于不会改变dna序列的可遗传变化。

• improving technologies are now providing a broader look at the epigenetic changes linked to environment and behavior.

  日新月异的科技使得我们可以用更广阔的视野看待与环境和行为相联系的表观遗传变化。

• another complication arises because some traits, particularly those associated with seed production, don’t seem to dabble in epigenetic inheritance.

  在研究过程中还出现了另外一个复杂的问题，一些生物特征，尤其是那些与育种有关的特征，似乎与表观基因遗传并不相关。

• there is some evidence that the environment causes epigenetic changes that make people more susceptible to asthma.

  某些证据表明，环境因素会导致致使人类更易患上哮喘的表观遗传（epigenetic）变异。

• when animals are cloned, epigenetic changes can occur.

  克隆动物后，表观遗传的变化就会发生。

• andrew hudson at the university of edinburgh says there is a clear implication that 「dna methylation and epigenetic changes are important in evolution.」

  爱丁堡大学的andrewhudson表示，这明显意味着「dna甲基化和表观基因变异在进化中是非常重要的」。

• another paper, from january 2010, shows that the genes in art embryos bear different epigenetic marks than non-art embryos.

  另一篇是发表于2010年1月的论文，表明art胚胎里的基因和非art基因比，承受着不同的表观遗传学标志物.

• drug companies have developed some treatments that reset epigenetic information in cancerous cells, making them revert back to being healthy.

  各大制药公司已研发出一些治疗方法，可以将癌细胞中的表观遗传信息进行复位，使这些癌细胞回复到健康状态。

• epigenetic changes are thought to be a major factor in our risk of developing cancer, an area that has attracted an enormous amount of research.

  表观遗传变异被视为我们患上癌癥的一个主要因素，而癌癥的研究领域一直以来都吸引了大量的研究。