ribosome
n. [细胞][生化] 核糖体;[生化] 核蛋白体
2026-03-22 06:47 浏览次数 19
n. [细胞][生化] 核糖体;[生化] 核蛋白体
"the ribosome is the site of protein synthesis"
mitochondrial ribosome线粒体核蛋白体
ribosome cycle核蛋白体循环
ribosome dna核糖体dna
ribosome profilingRibosome profiling (also known as polysome profiling) is a technique that uses messenger RNA (mRNA) to determine what proteins are being translated. It produces a “global snapshot” of all the ribosomes active in a cell at a particular moment.
cytoplasmic ribosome胞质核糖体
active ribosome活性核蛋白体
prokaryotic ribosome原核核蛋白体
bound ribosome固着核糖体
a single mutation, a different sequence in the dna, causes the ribosome to use a different amino acid when it builds the lysozyme molecule.
单一突变,dna序列发生变化,会造成核糖体在构建溶解酵素分子时使用不同的氨基酸。
chief among them will be a full-on mirror ribosome—no easy task, since the ribosome is a mountain of a molecule, protein and rna, dating from a time before luca.
其中最主要的工具将是完全的镜像核糖体——这个任务可不轻松,因为核糖体是分子、蛋白和rna的集合体,其形成的时间甚至可以上溯到露卡时代之前。
the answer, dr. berg said, is that the active core of the ribosome is made of rna.
答案就是核糖体的起作用的核心是由rna组成的。
he has managed to synthesise all the rna components in such a way that, when they are mixed with natural ribosome proteins, they form working ribosomes.
他成功合成了全部rna成分,使得当他们与天然核糖体蛋白质混合时,他们组成活的核糖体。
in a news release, the swedish academy said the three were being honored 「for having showed what the ribosome looks like and how it functions at the atomic level.」
在一篇报道中,瑞典科学院称赞三位科学家:「说明了核糖体的构型以及在原子层面是如何作用的。」
just type the protein databank id number for the ribosome that you want to look at, and then start exploring.
只要输入你想要查看的核糖体id号,就可以开始你的探索之旅。
the protein seems to have been added later, which means the ribosome is 「an rna-based machine that evolved the ability to make proteins.」
berg博士说,蛋白质似乎是后来加上去的。 也就是说,核糖体是一个rna为基础的工厂,进化出制造蛋白质的能力。
many research teams have been striving to determine the structure of a eukaryote ribosome (see 「structures of desire」).
许多研究小组力求确定一个真核核糖的结构(看到向往的结构)。
the ribosome finds the appropriate amino acid for each 「letter」 and assembles them head-to-tail in sequence; other 「letters」 indicate when to start and when to stop.
核糖体找到每个 「字母」的适当的氨基酸,并将它们首尾相连,组成一个序列;其他 「字母」表示何时开始以及何时停止。
the ribosome research, the academy said, is being used to develop new antibiotics.
瑞典科学院说明,核糖体的研究,为新的抗生素的创造,铺平道路。
now, after years of work and amid fierce competition from rival teams, a structure for the eukaryotic ribosome has been unveiled.
经过多年的研究,真核状态核糖(核蛋白体)的结构被揭露了出来。
plasmodium falciparum, which causes malaria, might also lead to the development of drugs that specifically target the ribosome in these organisms.
研究寄生虫的核糖,如可导致昏睡病等疾病的锥体虫,可导致疟疾的恶性疟原虫,将有可能推进针对这些生物核糖的专门药物的开发。
the ribosome reads the a/c/t/g code in groups of three, allowing us to derive a 64-letter 「alphabet.」
核糖体以三个一组的形式读取a/c/t/g编码,这样我们可以得出一个64字母的 「字母表」。
the hope is that understanding the ribosome's structure will lead to a deeper understanding of the basic biology by which the ribosome makes proteins.
希望在于对核糖结构的了解能使人们更深入了解核糖制造蛋白质的基本生物学原理。
a hacked ribosome modified to handle both normal and mirror amino acids could crank out the stuff on an industrial scale.
但现在,利用可以处理正常和镜像蛋白质的改造核糖体就能以工业化规模粗略合成原料药。
they then used 「very fast and very gentle」 purification techniques to obtain ribosome crystals, from which they worked out the structure with x-rays.
然后他们用「非常快速温和」的凈化技术得到核糖晶体,通过用x射线研究晶体绘出核糖的结构。
though they haven’t published their results yet, last year his team got a synthetic ribosome to self-assemble and produce luciferase, the protein that makes fireflies glow.
去年,丘奇的研究团队通过自组装获得了合成核糖体,并产生了荧光素酶,这种蛋白质可以使萤火虫发光。
the professor says ribosome is central to the survival of any organism.
这位教授说,核糖体是至关重要的,任何生物的生存。
a manufacturing ribosome would be great, but a fully domesticated mirror cell—able to synthesize more-complicated stuff—would change everything.
生产型的核糖体固然很棒,但完全驯化的镜像细胞不仅能合成更为复杂的药物原料,甚至还能改变一切。
dr. steitz is the co-founder of the company rib-x pharmaceuticals of , formed to apply the ribosome research to develop and commercialize drugs for the treatment of .
stertz博士是位于纽黑文的rib-x药物公司的创始人之一。 该公司将核糖体研究的成果用于研发和生产药物,用以解决多重耐药性的细菌疾病的治疗。