antisense rna
反义RNA
2025-06-25 21:51 浏览次数 5
反义RNA
conclusion dual-target antisense rna targeting the x and p regions in the genome of hbv inhibits the replication and expression of hbv, significantly stronger than single-target antisense-rna.
结论hbvx、p双靶区反义rna对乙型肝炎病毒转基因鼠有显着抗hbv作用,且在作用效率和作用时间上优于单靶区反义rna。
conclusion cd147 antisense rna can inhibit invasion and tumorigenesis of ovarian cancer cells and cd147 may become a new drug target of tumor therapy.
结论cd147反义核酸能抑制卵巢癌的转移和成瘤,因而有可能成为卵巢癌的治疗的药物靶点。
objective:to study the effect of vegf antisense rna on the proliferation activity and apoptosis of human pituitary adenoma cells in vitro.
目的:研究血管内皮生长因子(vegf)反义rna对体外培养人脑垂体瘤细胞增殖和凋亡的影响。
conclusion:the results suggest that cd40 antisense rna can inhibit normal function of cd40 and induce apoptosis of cd40 bearing cells.
结论:提示cd40反义rna特异性阻断了cd40正常功能的发挥,导致细胞凋亡。
objective to investigate the effect of dual-target antisense rna of hepatitis b virus (hbv) targeted to x and p region on replication and expression of hbv gene in hbv transgenic mice.
目的探讨针对乙型肝炎病毒(hbv)x、p双靶区反义rna对乙型肝炎病毒转基因小鼠hbv复制和表达的影响。
antisense rna now being used in an attempt to provide an agent against bacteriophage genes to help in the constant struggle between lactic acid bacteria and their phages.
现在正在使用反义rna技术试图提供一种抗噬菌体遗传因子的试剂,从而帮助乳酸菌和它们的噬菌体进行长期不问断的斗争。
when sense and antisense rna molecules meet, they bind to each other and form double-stranded rna.
当感觉和抗感觉rna分子相遇的时候,他们结合在一起形成双链的rna。
the antisense rna technique can be efficiently used to identify previously un known genes and produce new types of plant by down-regulation of endogenous plant genes.
反义rna技术是一种有效的遗传操纵手段,可用于鑒别克隆基因的功能并培养新型的植物品种。
conclusion the recombinant adenovirus carrying antisense rna to ccr5 has laid down a good foundation for studying its inhibiting effect on hiv-1 infection.
结论成功地构建了携带ccr5反义rna重组腺病毒载体,为研究其抗hiv1的作用打下基础。
antiviral activitity of the antisense rna was evaluated by cytopathic effect using cultured ibrs2 cell and anti- ibrs2 cell infected by tgev respectively, and the inhibitory rate was about 50%.
通过tgev分别感染ibrs2和ibrs2抗性细胞产生的病变,结果表明该反义rna对病毒的复制有抑制作用,其抑制率近50%。
this paper presents the definition and action mechanism of antisense rna; besides, the paper reviews antisense rna technology and its application in agricultural field.
介绍了反义rna的概念及作用机理,对反义rna技术及其在农业领域的应用进行了概述。
this is binding in stand-by, you might say. but we can show that antisense rna competes with the ribosomes to be able to attach to this stand-by site as well.
你也许会说这是具有约束力的準备,但是,我们能够证实反义rna竞争核糖体通过预备的位点。
aim: to construct the recombinant adenoviral vector carrying antisense rna to chemokine receptors ccr5 and cxcr4 and to obtain recombinant adenovirus, which will be used to resist hiv 1 infection.
目的:构建趋化因子受体ccr5 ,cxcr4 双靶区反义rna重组载体并获取重组腺病毒以用于抗hiv1基因治疗的研究。
methods vegf antisense rna was transfected into human esophageal cancer te-1 cell. cell proliferation was detected by mtt assay.
方法用脂质体法将血管内皮细胞生长因子反义rna转染到人食管癌te-1细胞,噻唑蓝还原法检测细胞增殖情况;
objective to explore the effect of antisense rna on hepatitis b virus (hbv) replication and antigen synthesis.
目的了解反义乙型肝炎病毒(hbv)基因转移、表达的抗hbv作用。
aim: to investigate the effect of antisense rna of hepatitis b virus (hbv) in x region and p region on replication and expression of hbv gene in hbv transgenic mice.
目的:探讨针对乙型肝炎病毒(hbv)x区反义rna和p区反义rna对乙型肝炎转基因小鼠hbv复制和表达的影响。
methods antisense rna expression vector corresponding to lr precursor (lrp) was constructed by dna recombinant technique, and transferred into gastric cancer mdr cells sgc7901/vcr with lipofect amine.
方法应用dna重组技术构建lr前体蛋白(lrp)的反义rna表达载体,并借助脂质体将其导入胃癌mdr细胞sgc790 1vcr中。
construction of recombinant retrovirus vector carrying dual target antisense rna of hbv is in the foundation of construction of recombinant retrovirus vector carrying sing target in similar ways.
为探索在真核细胞内转录表达hbv反义rna的方法及研究多基因区抗病毒治疗和抗变异病毒打下基础。
aim:to construct eukaryotic antisense rna expression vector of cd147 and probe into a new method to treat invasion and transfer of osteosarcoma.
目的:构建cd147反义rna表达质粒载体,探索治疗骨肉瘤侵袭和转移的新方法。
objective to observe the effect of proliferating cell nuclear antigen (pcna) antisense rna on the growth characteristics of human gastric cancer cell.
目的观察增殖细胞核抗原(pcna)基因反义rna表达质粒对人胃癌细胞生长特性的影响,探讨其抗肿瘤作用。
purpose : to study the effects of recombinant adenovirus encoding human cox-2 antisense rna on proliferation of human esophageal carcinoma cell line ec9706 in different time point.
目的:探讨环氧合酶-2(cox-2)反义rna在不同时间点对人食管癌细胞系ec9706生长的影响。
it has been shown that this occurs in bacteria in that antisense rna sets up base pairs with a certain messenger rna (m-rna) precisely where the ribosomes would start their reading.
在细菌的细胞分离增殖活动中已被证实,反义rna通过精确的堿基配对从而在此信使rna的核糖体开始进行转录与翻译活动。
results:after the transfection, antisense rna had been successfully expressed respectively, and nk cells activity had been improved about 15%.
结果:转染后反义rna均得到高水平表达,并使nk细胞的杀伤活性提高约15%。
conclusion using vegf antisense rna to block endogenous vegf production is an operative gene therapy in treating tumor through anti-angiogenesis.
结论vegf反义rna治疗是一种有效的肿瘤抗血管生成基因治疗方法。
it was investigated that over-expression of p33ing1 could promote apoptosis induced by lack of serum , and transfection antisense rna could suppress apoptosis induced by lack of serum.
有研究表明p33ing1的过表达可促进由「血清饑饿」诱导的细胞凋亡,而转染反义rna则可抑制「血清饑饿」导致的细胞凋亡。
objective to observe the effects of antisense rna of connective tissue growth factor (ctgf) on rat liver fibrosis.
目的观察结缔组织生长因子(ctgf)反义rna对实验性肝纤维化的影响。
with the discovery of antisense rna and further research, antisense rna technique has been applied in the study of gene regulation.
随着反义rna的发现及对其研究的深入,反义rna技术已被广泛应用于基因调控的研究中。