objectiveto establish an experimental cancer cachectic model, and observe the nutritional and hormonal disorders.
目的建立一种癌性恶病质动物模型,并观察其营养指标和体液因子的变化。
objective: to investigate the expression of ubiquitin-proteasome pathway in skeletal muscle of cachectic mice and the effect of indomethacin(ind) on it.
目的:研究泛素蛋白质酶途径在癌性恶病质小鼠骨骼肌中的表达以及吲哚美辛(ind)对其的调控作用。
previous studies have reported that il-10 production was significantly elevated in cachectic patients, and it has been confirmed that polymorphisms of the il-10 gene could influence its expression.