ed-71 improved the expression of p27kip1. conclusioned-71 treatment could inhibit proliferation of human liver carcinoma cell hepg2, cause partial differentiation and induce the expression of p27kip1.
结论ed-71抑制人肝癌细胞株hepg2的生长,诱导人肝癌细胞分化,使细胞阻滞于g1期,可能与ed-71诱导人肝癌细胞中抑癌基因p27kip1蛋白的表达有关。