英语释义

• a gene that causes normal cells to change into cancerous tumor cells

片语

oncogene site癌基因位点

oncogene shock导致出现癌基因休克

oncogene activation癌基因激活

Oncogene proteins癌基因蛋白质类

cell oncogene癌基因

suppressor oncogene癌抑制基因

carcinogene致癌基因

recessive oncogene隐性癌基因

suppression oncogene抑癌基因

oncogene c癌基因c

英汉例句

• the discovery of oncogene and tumor suppressor gene has deepened human beings understanding of the mechanisms of cell cycle and cell apoptosis as well as the mechanisms of tumorigenesis.

  癌基因，肿瘤抑制基因的发现促进了对细胞周期及细胞凋亡机制的深入理解。 使人们对肿瘤发生和发展的认识也日趋深入。

• mutational activation of the braf oncogene is the most common genetic alteration in cutaneous melanoma.

  braf癌基因突变的激活是皮肤黑色素瘤最常见的基因改变。

• vegf121 expression is induced by hypoxia, inflammatory cytokines and through oncogene products in tumors (1-3).

  vegf121的表达受到组织缺氧，炎癥因子和肿瘤组织产生的致癌基因的诱导（1-3）。

• conclusion:the effect of weiyankang plus gastrone on precancerosis of gastric cancer may due to repress the abnormal expression of oncogene proteins in gastric mucosa.

  结论：胃炎康加维酶素可能是通过抑制胃黏膜癌基因蛋白的异常表达而发挥治疗胃癌前病变的作用。

• here we perform genome-wide rna-interference screening to identify 17 genes required for an activated braf oncogene (brafv600e) to block proliferation of human primary fibroblasts and melanocytes.

  在这里，我们进行全基因组的rna干涉筛选来确定：实现激活braf基因（brafv600e）进而阻止人类初级成纤维细胞和黑素细胞增值这一功能所需的17个基因。

• it has been proved that the occurrence of oncogenesis is in close relationship with the oncogene activation, the tumor suppressor gene inactivation and the disorder of cell cycle modulation.

  目前在分子水平上的研究显示肿瘤的发生与癌基因的激活和抑癌基因的失活以及细胞周期调节失控密切相关。

• conclusion telomerase activity may play an important role during cervical carcinogenesis, and telomerase activity is strongly associated with hpv infection and oncogene in uterine cervical lesions.

  结论端粒酶活性在宫颈癌发生中可能起到重要作用，在子宫颈损伤中端粒酶激活与hpv感染及其致癌基因的表达密切相关；

• somatic alterations within the oncogenome underlie the genesis and progression of most human tumors, by causing oncogene activation or tumor suppressor gene inactivation.

  大部分人类肿瘤是由基因组中的体细胞性改变所导致的癌基因激活或抑癌基因失活所引发的。

• study the effects of oncogene on genesis and development of acp and try to find out the evidences providing for proof of diagnosis, evaluating prognosis and guiding the treatment of acp.

  目的研究癌基因在胰腺癌发生发展中的作用，为胰腺癌的诊断、评估预后和指导治疗提供依据。

• expression of an oncogene in a primary cell can, paradoxically, block proliferation by inducing senescence or apoptosis through pathways that remain to be elucidated.

  初始细胞的癌基因的表达往往会通过诱导细胞凋亡、衰老来阻止细胞的增值的，而其实现上述功能的具体途径仍有待澄清。

• the influencing of some oncogene and anti-oncogene to the expression and activity of hif-1 determines neoplastic prognosis ultimately.

  而某些癌基因和抑癌基因对hif-1表达及活性的影响最终决定着肿瘤的预后。

• facing the mechanisms of molecular biology of hpv e6 oncogene induced cervical carcinomas, this article is to illustrate the relationship between e6 oncogene and cervical carcinoma.

  针对e6癌基因诱导宫颈癌发生的分子生物学机制综述近年来e6癌基因与宫颈癌关系方面的研究进展。

• conclusion:telomerase activity may play an important role in cervical carcinogenesis, and telomerase activity is strongly associated with hpv infection and oncogene in uterine cervical lesions.

  结论：端粒酶活性在宫颈癌发生中可能起到重要作用，在子宫颈损伤中端粒酶激活与hpv感染及其致癌基因的表达密切相关；

• elevated levels of odc gene products are consistantly detected in some oncogene transformed cell lines and virtually all animal tumors.

  在一些癌基因的转化细胞系和几乎所有的动物肿瘤中均有odc基因产物的异常升高。

• quite a few kinds of genes such as susceptibility gene, oncogene and tumor suppressor genes have been found with implications for diagnosis, therapy and prognosis.

  其中涉及多种基因异常，包括易感基因、癌基因、抑癌基因等，对于乳腺癌的诊断、治疗及预后判断均具有提示作用。

• besides the outcome of immunosuppression, the effects of transplantation itself, such as oncogene chimera, transition of carcinogenic virus and so on, can not be neglected.

  其机理除了应用免疫抑制治疗所带来的后果外，也不能忽视移植术本身带来的影响，如癌基因嵌合、致癌病毒的转移等。

• to investigate relationship between changes of oncogene expressions and radiation damage in glioma cell lines.

  目的：探讨癌基因表达的变化与辐射性细胞放射损伤的关系。

• more and more evidence indicated that the formation of tumor is due to multi factors with oncogene activation and anti oncogene inactivation.

  越来越多的证据表明，肿瘤的发生是多因素作用的结果，与癌基因的激活与抑癌基因的失活有关。