英语释义

• a mutation due to an intramolecular reorganization of a gene

片语

A point mutation点突变

single point mutation单点突变

point t mutation点突变

point gene mutation点突变

accepted point mutation受点突变

Point Accepted MutationA PAM is a point accepted mutation, also known as a percent accepted mutatio A PAM is a set of matrices used to score sequence alignment

One-Point Mutation单点突变

dyadic floating-point supplementary mutation二元浮点补码变异

point mutation activation点激活突变

英汉例句

• This single - point mutation engages the leg - making apparatus of the embryo fly to build a leg where its antenna should be.

  这个单点突变搅乱了果蝇胚胎的足肢生成装置，在原本应该是触角的地方生出一条腿来。

• The results suggested that AIV 178 isolate was amantadine resistant, and the position 31 amino acid point mutation in M2 protein may confer the resistance.

  结果表明AIV 178分离株具有对金刚烷胺的耐药性，而且M2蛋白的第31位氨基酸突变可能与此有关。

• AIM: To investigate the relationship between the point mutation of ABCB4 gene and intrahepatic cholestasis of pregnancy (ICP).

  目的：探讨ABCB 4基因点突变与妊娠期肝内胆汁淤积癥(ICP)发病的关系。

• In BCR-ABL fusion gene negative myeloproliferative diseases, the discovery of JAK2V617F point mutation is an important landmark.

  在BCR- ABL阴性的骨髓增殖性疾病的发病机制中，JAK2V 617 F点突变的发现是一个重大的突破。

• No p16 gene point mutation was detected.

  所有标本未检出点突变。

• Conclusion the site specific point mutation system can modify human gene in vitro more accurately. It is useful in the setting up of animal models.

  结论体外定点突变系统可以对基因进行精细的修饰，为建立更精确地模拟人类疾病的动物模型打下基础。

• Missense mutation a point mutation that causes a change in one amino acid of a protein.

  错义突变引起蛋白质中一个氨基酸变化的点突变。

• Out of other 6 IMF patients without JAK2V617F point mutation only 1 patient had thrombosis, and lower counts of platelets in perepheral blood and megakaryocytes in bone marrow.

  另6例JAK2V617F点突变阴性患者仅1例有血栓史，血小板数目及骨髓巨核细胞数目相对较低。

• Conditional gene knock-out is a new technique set up more than ten years ago. This technique can change intravital genetic information and introduce point mutation into animal body precisely.

  条件基因敲除技术是近十多年来发展出来的新技术，它可以通过简单的基因敲除改变活体的遗传信息，可以精确的在动物体内引入点突变。

• The point mutation detection rate of hair follicles was higher than that of blood. So, hair follicles have the potent clinical application value for the genetic analysis of mitochondrial diseases.

  毛球标本的线粒体点突变检测率高于血液，因此在线粒体相关疾病的基因分析中具有较高的临床应用价值。

• Objective To investigate the relationship between the point mutation of ABCB4 gene exon 23 and the intrahepatic cholestasis of pregnancy (ICP).

  目的：探讨ABCB4基因外显子23点突变与妊娠期肝内胆汁淤积癥（ICP）发病的关系。

• Objective To screen the point mutation at the codon 54(GGC54GAC) in the first exon of the mannan binding lectin (MBL) gene in Hans from Guangdong.

  目的对广东地区汉族人群的甘露聚糖结合凝集素结构基因第一外显子第54位密码点突变（GGC54GAC）进行初步筛查。

• Methods:The method for MBL point mutation detection(PCR-RFLP) was Established with self-designed primers according to MBL genomic sequence;

  方法：根据MBL基因序列设计引物建立MBL基因点突变检测方法即PCR -RFLP ；

• Twenty cases(20/31) were selected randomly for DNA sequencing. No point mutation of ABCB4 gene exon 23 were detected.

  随机挑选20例标本测定外显子23的DNA序列，未发现点突变。