what drugs alter prothrombin time by interacting with warfarin levels ( pharmacokinetics )?

2哪些药物可通过影响华法林水平改变凝血酶原时间（药代动力学角度）?。

there was no significant difference in platelet count, plasma prothrombin time and plasma viscosity between treatment group and control group ( p > 0.05) .

治疗组血小板计数、凝血酶原时间及血浆黏度变化与对照组相似（p>0.05）。

in large-dose group, the prothrombin time was prolonged and the fibrinogen level was decreased after the treatment(p0.05).

大剂量组治疗后凝血酶原时间延长、纤维蛋白原降低（p0.05）。

objective to explore effects of blood platelets and prothrombin time on mifepristone.

目的探讨米非司酮对血小板、血浆凝血酶原时间的影响。

after hbo therapy the levels of prothrombin time activity and aptt did not change significantly at various time points ( p > 0. 05 ).

hbo治疗结束，各个时间点的凝血酶原时间活动度和aptt两项指标与治疗前比较，差异无统计学意义（p>0．05）。

objective:to investigate the part influence factors of prothrombin time assay.

目的：探讨凝血酶原时间测定的部分影响因素。

methods: infrared turbidimetric method was used to estimate platelet aggregation, active partial thromboplastin time (aptt) , prothrombin time ( ft) and thrombin time (tt);

方法：红外比浊法测定血小板聚集率、凝血酶原时间（pt）、凝血酶时间（tt）、活化部分凝血活酶时间（aptt）；

method to check the prothrombin time(pt) and prothrombin time ratio(ptr) in deferent period, make the pt 1~1.5 times than its normal result using warfarin.

方法在心脏机械瓣膜替换术后不同时间段定期复查凝血酶原时间（pt）及凝血酶原时间比值（ptr），按其正常值的1~1.5倍给以华法林治疗。

conclusions:①among all the clinical parameters, the major risk factors affecting prognosis of severe hepatitis included age, serum bilirubin level, prothrombin time and simultaneous encephalopathy.

结论：①重型肝炎患者入院时的临床参数中，年龄、血清胆红素、凝血酶原时间、肝性脑病为影响预后的主要危险因素。

prothrombin time and international normalized ratio should be carefully monitored in patients concurrently administered istodax and coumadin derivatives.

凝血酶原时间和国际标準化比值应仔细监测患者同时管理istodax和香豆衍生物。

objectives: using normal plasmas and criterion plasmas to establish a kind of accurate and feasible method that could measure international normalized ratio (inr) of prothrombin time (pt).

目的：利用正常血浆和定标血浆，建立一种準确可靠、易于实验室开展的凝血酶原时间国际标準化比值检测方法。

the majority of patients with ascites due to cirrhosis have prolongation of the prothrombin time and some degree of thrombocytopenia.

大多数肝硬化腹水的患者凝血酶原时间延长并有一定程度的血小板减少。

the blood coagulative system in three groups was evaluated by testing platelet count (plc), active part thrombin time (aptt), prothrombin time (pt), thrombin time (tt), fibrinogen(fib).

血小板计数（plc） ，活化部分凝血活酶时间（aptt）、凝血酶原时间（pt）、凝血酶时间（tt）和纤维蛋白原定量（fib）。

the result of liver function, renal function, electrolyte, prothrombin time activity (pta), blood routine before and after the treatment were analyzed.

比较了血浆置换前后患者临床癥状、肝肾功能、电解质、凝血酶原活动度、血常规变化等。

objective to explore the clinical significance of platelet, prothrombin time , activated partial thromboplastin time , thrombin time , plasma fibrinogen for parturient women.

目的探讨临产孕妇血小板、凝血酶原时间、活化部分凝血活酶时间、凝血酶时间、纤维蛋白原检测的临床意义。

in high-dose group, the prothrombin time of was prolonged and the fibrinogen level was decreased after the lmwh treatment(p0.05).

大剂量组治疗后凝血酶原时间延长、纤维蛋白原降低（p0.05）。

laboratory: increase prothrombin time (pt).

实验室检查：凝血酶原时间（pt）延长。

plasma prothrombin time (pt), activate part plasma prothrombin time (aptt), prothrombin time (tt) , fibrinogen (fib) the level of fasting blood glucose (glu) are tested separately.

分别测定血浆凝血酶原时间（pt）、活化部分凝血酶原时间（aptt）、凝血酶时间（tt），纤维蛋白原（fib）、血清空腹血糖（glu）水平。

methed: 167 cases of valve replacement vere followed - up to research the prothrombin time for 1 - 8 years.

方法：对167例心脏机械瓣替换术的病人进行1～8年的凝血酶原时间随访研究。

however, there was no significant difference in the total bilirubin and prothrombin time in either group during the observation periods.

然而，观察期间在总胆红素和凝血酶原时间方面两组之间没有显着差异。

the prothrombin time pt and the activated partial thromboplastin time aptt were determined with coagulation method.

用凝固法测定血浆凝血酶原时间及活化部分凝血活酶时间。