the depression model of rat was established by chronic mild stress stimulation combined with single feed. the anti-depression effect of zjdz decoction was studied.
采用慢性缓和性应激和孤养建立抑郁模型,观测镇惊定志合剂的抗抑郁效果。
objectiveto investigate the alteration of behavior, such as spontaneous movement, spatial memory ability and cholinergic m receptors in the brain of mice subjected to chronic mild stress (cms).
用自发运动和水迷宫评定行为改变,用放射性配基法测定皮层、海马、下丘脑和小脑的m受体改变。
objective to explore the effect of chronic mild stress on the expression of 5-hydroxytryptamine receptor(5-htr)in hippocampus of pregnant rats.
目的探讨慢性温和应激后孕鼠脑内海马区5-羟色胺受体(5-htr)表达量的变化。
chronic stress is the primary inducement for depression. chronic mild stress model is a idea model for the study of depression.
而慢性应激是抑郁癥的主要发病诱因,慢性应激抑郁癥模型被公认为是研究抑郁癥的理想模型。
mice in the chronic mild stress group and 5-ht injured group showed obvious depressive symptoms:①body mass in mice of both groups increased slowly, and the increasing amount significantly decreased.
羟色胺损毁组和慢性刺激组的小鼠表现出多项抑郁癥状:①两者模型小鼠体质量增加缓慢、增加量明显减少。