A low GFR is a dangerous sign of existing diabetic kidney disease that can progress to kidney failure, also called end-stage kidney disease, which requires dialysis or kidney transplantation.
It suggests that elevated GFR might be one of the abnormal characteristics of renal functional changes in early IDDM.
提示GF R增高是早期IDDM肾脏功能异常表现的特点之一。
The investigators speculate that, based on the study's findings, it is possible that GFR provides a better marker than concomitantly measured cardiovascular risk factors.
研究者推测,根据此研究发现,GFR可以比其它现有的心血管风险因素提供更好的标记。
Patients with microalbuminuria and DR showed the fastest GFR decline.
微量白蛋白尿和DR患者GFR下降最快。
The results suggest that GFR and ERPF are sensitive and efficient renal function indicators, in both diagnosis and treatment.
结果表明GFR及ERPF测定是了解病情演变及观察疗效灵敏而有效的肾功能指标。
Relative analysis demonstrated NO in renal tissue was positively correlated with GFR but negatively correlated with urinary protein contents and basement membrane thickness.
相关分析表明,肾组织中NO与GF R呈正相关,与尿蛋白排泄量、基底膜厚度呈负相关。
Reduced estimated GFR was the strongest predictor of end-stage renal disease in fully adjusted analysis, and estimated GFR modified the relationship between FGF-23 and risk of end-stage renal disease.
Intensive multifactorial intervention in patients with type 2 diabetes with microalbuminuria nearly halved the progression of proteinuria but did not alter the rate of GFR decline.
It is still valid but if you find someone with an estimated GFR below 60 without microalbuminuria or macroalbuminuria then the story is that the risk for this patient is not elevated.