a layer of deeply pigmented gray matter in the midbrain; associated with the striate body; is involved in metabolic disturbances associated with Parkinson's disease and with Huntington's disease

conclusion reduced glutathione may have protective effect on apoptosis and oxidative stress of substantia nigra neurons in mptp induced pd mouse model.

结论还原型谷胱甘肽可能对mptp损伤的黑质多巴胺神经元凋亡有抗氧化保护作用。

the dopaminergic neurons in the dense right substantia nigra region disappeared nearly, and the surviving ones were atrophic in the model group.

模型组右侧黑质致密区内多巴胺能神经元几乎消失，残存细胞萎缩；

the changes of dopaminergic neurons in substantia nigra pars compact (snc) and ventral tegmental area (vta) in midbrain were studied using immunohistochemistry method.

用免疫组织化学方法研究中脑黑质致密区（snc）和腹侧被盖区（vta）多巴胺能神经元的变化。

results: th positive neurons and neurites in the right substantia nigra compacta (snc) and striatum of the rat model of pd were decreased(p0.01), which proved successful pd models.

结果：模型组大鼠右侧黑质致密部th阳性神经元及纹状体th阳性纤维明显减少（p0.01），证明模型制作成功。

results: after implantation, mapcs could survive and differentiate into neuron-kike cells in substantia nigra and striatum, including dopamine-neurons.

结果：多潜能成年祖细胞能移行入大鼠脑组织内并在中脑黑质和纹状体区分化为神经元样细胞。

the relationship of lateral habenula(lhb)and substantia nigra in the pain mechanism was investigated by extracellular recording.

本文采用细胞外记录方法探讨缰核与黑质在痛觉机制中的关系。

objective to study the mechanism of dopaminergic neuronal death in substantia nigra of parkinson「s disease (pd).

目的研究帕金森病（pd）黑质多巴胺神经元的死亡机理。

conclusion: nac can attenuate mptp-induced apoptosis of substantia nigra neurons through down-regulating oxidative stress and blocking jnk signaling cascade.

结论：nac能减少mptp诱导的小鼠黑质神经元凋亡，其机制与抗氧化及阻断jnk细胞凋亡通路的激活有关。

dopamine neurons in parts of the midbrain, such as the ventral tegmental area and substantia nigra pars compacta, play a vital role in the expectation of reward.

中脑的一些区域的多巴胺神经元，如腹侧被盖区和黑质致密部，在对奖赏期待中起关键作用。

initial results in a handful of patients suggested that symptoms had improved, and pet scans indicated some restoration in dopamine uptake in the striatum and substantia nigra .

这一小群患者的初步结果显示癥状得到改善，而正子断层扫描则指出，纹状体与黑质多巴胺的吸收也有些进步。

objective to study the substantia nigra apoptosis in parkinson disease (pd) model rats and the nigra neurons protective effect of resveratrol.

目的研究帕金森病（pd）动物模型黑质细胞的凋亡情况及白藜芦醇对神经的保护作用。

ultrastructure changes in substantia nigra and striatum after chronic ischemia have an effects on behavior of stereotypy and change function of dopamine system in rats.

慢性缺血大鼠在阿朴吗啡的作用下，刻板动作行为的积分会明显高于正常对照组，提示黑质和纹状体的多巴胺系统功能受到了干扰。

objective: to discuss the protective effect on dopaminergic neurons in substantia nigra of the parkinson s disease model mouse treated by electroacupuncture scalp point-through-point therapy.

目的：探讨头部电针透穴疗法对帕金森病模型大鼠黑质多巴胺能神经元的保护作用。

objective to explore the possibility of electroacupuncture (ea) for prevention of the injury of dopaminergic neurons in the substantia nigra of the rat with parkinson」s disease.

目的：探究电针防止帕金森病大鼠黑质多巴胺能神经元损伤的可能性。

following mptp intoxication, 2-dg uptake was increased in the substantia nigra and locus ceruleus. at the same time, obvious abnormal behavior of the animals was induced.

腹腔注射mptp后，模型组鼠的黑质和蓝斑区的2-dg摄取量较对照组鼠明显增加，并表现出明显的行为异常反应。

objective to study the effect of manganese on neuron-specific enolase (nse) activities in the caudate putamen nucleus and substantia nigra of filial rats during intrauterine exposure.

目的研究大鼠染锰后对子代幼鼠脑尾壳核、黑质烯醇化酶（nse）活力的影响。

results the typical dopaminergic neurons were observed at substantia nigra pars compacta in midbrain brain slices.

结果黑质致密部中脑脑片可见典型的多巴胺神经元形态，小胶质细胞呈典型的静息状态。

the immunohistochemical staining intensities of dopamine d1 receptor and dopamine d2 receptor in the striatum and substantia nigra of rat models were observed.

观察模型大鼠黑质和纹状体多巴胺d1受体和多巴胺d2受体免疫组织化学染色强度。

it is to explain that it is dopamine d2 acceptor that is involved in regulation of temporal epilepsy in substantia nigra rather than d1 acceptor.

说明在黑质中参与颞叶癫痫调节作用的主要是多巴胺d2受体而不是d1受体。

objective to study the effect of exposure to manganese in pregnant rats on the neuron specific enolase(nse)in the substantia nigra of their offsprings.

目的研究孕鼠染锰对其子代脑黑质中神经元特异性烯醇化酶（nse）的影响。