2026-03-22 12:30 浏览次数 17
糖配基
the chemical modification of sugar moiety in nucleoside or nucleotide is always an important way to discover new lead compounds with anti-viral, anti-tumor and other biological activities.
对核苷类化合物糖环部分的化学改造一直是发现新的具有抗病毒、抗肿瘤或其他生物活性的核苷类先导化合物的重要途径之一。
the lack of the sugar moiety could cause changes in the structure of the active site of the enzyme resulting in the observed modifications of the kms.
去除糖基会使葡萄糖氧化酵素的活化位构造改变,因而产生所观察到的km值变化。