conclusions the double suicide gene driven by kdr promoter has specific killing effect on kdr-expressing gastric tumor cells and venous endothelial cells in vitro.
结论kdr基因启动子可调控双自杀基因系统选择性杀伤表达kdr胃癌细胞及血管内皮细胞。
our results demonstrated that combined transfer of suicide gene and il-2 gene could inhibit the growth of established tumor in mice significantly and induce antitumor immunity of the host efficiently.
conclusion hsv-tk/gcv in combination with hcpt can enhance the lethal effect of suicide gene therapy against human bladder carcinoma cells and effectively induce apoptosis of the cells.
con-elusion:the suicide gene therapy system using an ovarian-specific promoter by polyethylenimine mediated transfection has a targeting killing activity on human ovarian cancer.
结论:多聚乙烯基亚胺介导的卵巢特异性启动子调控下的自杀基因对卵巢癌有靶向杀伤作用。
objective to determine the efficacy of adenovirus-mediated suicide gene transduction combined with prodrug 5-fluorocytosine (5fc) as a therapeutic protocol for pancreatic cancer.
目的探讨腺病毒介导自杀基因联合前药5fc对人胰腺癌的治疗作用。
conclusion the double suicide gene under the regulation of kdr promoter has specific killing effect on the kdr expressing endothelial cells and colorectal tumor cells.
结论kdr基因启动子可调控双自杀基因系统选择性杀伤表达kdr的血管?。
objective to study the effects e. coli purine nucleoside phosphorylase suicide gene on human gastric cancer mkn-45 cells as well as the bystander effect.
conclusion our results suggest that combined therapy with suicide gene and gm-csf gene transfer could directly eradicate established tumors and efficiently induce the antitumor immunity of the mice.
results double and single suicide gene transfer were both stably expressed in glc-82 cells . the cytotoxic effects of co-expressed tk-cd genes were superior than that of the single gene.