Objective: to study the effect of tumor necrosis factor (TNF) on hypermetabolism of skeletal muscle protein in burned rats with sepsis and evaluate its possible mechanism.
目的:研究肿瘤坏死因子(TNF)在烧伤脓毒癥大鼠骨骼肌蛋白高分解代谢中的作用,并探讨其可能的机制。
Studies suggest that, in sepsis, skeletal muscle protein catabolism and the ubiquitin-proteasome system are closely related.
研究认为脓毒癥大鼠骨骼肌蛋白高分解代谢与泛素-蛋白酶系统密切相关。
At present, the study about the impact of IL-15 in the role of skeletal muscle protein degradation on sepsis state is rare, and the mechanism is unclear.
目前关于IL - 15对脓毒癥状态下骨骼肌蛋白质分解代谢影响的研究罕见,机制尚不清楚。