botulinum neurotoxin is a type of neural paralysis toxin of great toxicity known to science and it can cause botulism both in humans and animals.
肉毒毒素是自然界中毒性极强的一类神经麻痹毒素,可引起人类和动物肉毒中毒。
for example, the mouse assay that is still the gold standard for botulinum neurotoxin detection (3) is both costly and difficult to deploy.
比如,对于肉毒(桿)神经毒素的检测来说,老鼠的化验仍然是花费巨大并且很难普及的金本位(公认衡量标準)。
aim: in order to learn nucleotide sequences of clostridium botulinum neurotoxin type a(bont/a) and deduce its amino acid sequences, the authors analyzed the gene of the toxin .
对国内a型肉毒桿菌毒素基因测序,分析了解毒素基因结构并推测其氨基酸序列。
conclusion the pcr system is specific and sensitive for the identification of botulinum neurotoxin type a.
结论:建立的检测方法特异性强、灵敏度高,可以用于a型肉毒毒素基因的快速筛查。